There are three main areas of research that we are doing in our 'Institute of Human-Environment Interface Biology (IHEIB)'.

First, we are investigating how various environmental stimuli from external environment cause skin aging, and we are studying prevention and treatment of skin aging.

We are investigating the effects of ultraviolet radiation, which are the main cause of skin aging, on the skin, and also examining the effect of thermal changes on skin aging. In addition, we are investigating various environmental stimuli known to cause the aging of skin over a long period of time.

Second, we are identifying the various components of the skin such as collagen fibers, elastic fibers, proteoglycans, and glycosaminglycans in aging skin, to clarify what causes them, and to identify underlying molecular mechanisms. Based on the results, we are developing methods to prevent and treat skin aging process.

We have developed methods to rejuvenate the aged skin levels, and use them in clinical research and product development.

Third, recent studies have revealed that the effects of skin aging on the function of other organs in the human body.

Skin is not simply a physical barrier that protects our bodies. Skin is an endocrine organ that secretes various hormones and secretes various physiologically active substances. Do you know that when your skin ages and its function is reduced, it can cause serious abnormalities in the functions of other organs of the human body? We are investigating the associations between skin and brain, blood vessels and metabolic syndrome. We are studying how the health of skin is important to the health of our body. We are developing ways to improve the health of other organs of our body by modulating the skin.