150. Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses
SC Kim*, JW Park, HY Seo, MJ Kim, JH Park, GH Kim, JO Lee, YK Shin, JM Bae, BK Koo, SY Jeong, and JL Ku*
149. Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types
Seo HY, Kim SC*, Roh WL, Shin YK, Kim S, Kim DW, Kim TM, Ku JL*
148. Novel cancer stem cell marker MVP enhances temozolomide-resistance in glioblastoma
Kum Hee Noh*, Song-Hee Lee, Haeri Lee, Ae Jin Jeong, Kyu Oh Kim, Hyun Mu Shin, Hang-Rae Kim, Myung-Jin Park, Jong Bae Park, Jiyoung Lee, Sang-Kyu Ye
147. Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses
Soon-Chan Kim*, Ji Won Park, Ha-Young Seo, Minjung Kim, Jae-Hyeon Park, Ga-Hye Kim, Ja Oh Lee, Young-Kyoung Shin*, Jeong Mo Bae, Bon-Kyoung Koo, Seung-Yong Jeong, Ja-Lok Ku*
146. Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse.
Bonah Kim, Hee Young Kim, Won-Woo Lee*
145. Urine 5-Eicosatetraenoic Acids as Diagnostic Markers for Obstructive Sleep Apnea
신현우*, 박종완*, Cho, K ,이재서, Hong, IH , Cho, SH , Kim, SW , Kim, J , So, D ,조주연
144. Tumor-intrinsic FABP5 is a novel driver for colon cancer cell growth via the HIF-1 signaling pathway.
Seo J, Yun J, Fukuda J, 전양숙*
143. Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling
백선하*, Shin, HY ,Han, KS , Park, HW , Hong, YH , Kim, Y , Moon, HE , Park, KW , Park, HR , Lee, CJ , Lee, K , Kim, SJ , Heo, MS , Park, SH , Kim, DG
142. Thermosensitivity of the voltage-dependent activation of calcium homeostasis modulator 1 (calhm1) ion channel
김성준*,최성우*,Jeon, YK , Kwon, JW , Woo, J , Choi, SW ,김상정
141. The N-terminal cysteine is a dual sensor of oxygen and oxidative stress
권용태*,Heo, AJ , Kim, SB , Ji, CH , Han, D , Lee, SJ , Lee, SH , Lee, MJ , Lee, JS , Ciechanover, A , Kim, BY
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2021,
118,
50,
SCI(E) Link
140. The Effect of Neddylation Blockade on Slug-Dependent Cancer Cell Migration Is Regulated by p53 Mutation Status
전양숙*,Kim, Y , Park, JB , Fukuda, J , Watanabe, M
139. Stereotypic neutralizing VH antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals
Sang Il Kim*, Jinsung Noh, Sujeong Kim, Younggeun Choi, Duck Kyun Yoo*, Yonghee Lee, Hyunho Lee, Jongtak Jung, Chang Kyung Kang, Kyoung-Ho Song, Pyoeng Gyun Choe, Hong Bin Kim, Eu Suk Kim, Nam-Joong Kim, Moon-Woo Seong, Wan Beom Park, Myoung-don Oh, Sunghoon Kwon, Junho Chung
138. STAT3 activation in microglia exacerbates hippocampal neuronal apoptosis in diabetic brains
예상규*, 조정현*,Yun, JH , Lee, DH , Jeong, HS ,김혜선
137. SARS-CoV-2 Infection of Airway Epithelial Cells
신현우*, Ryu, G
136. Regulatory Role of Zinc in Immune Cell Signaling
Bonah Kim, Won-Woo Lee*
135. Reduced nNOS activity is responsible for impaired fatty acid-dependent mitochondrial oxygen consumption in atrial myocardium from hypertensive rat
Yin Hua Zhang*,Wu, Y. N.,Jin, C. L.,Jang, J. H.,Zhao, Z. H.,Kim, S. J.
134. Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells
윤홍덕*,이한터,이일환,김재환,이상호,곽소정,서민영,황인영,강부경,차선신,이병일,이상언,최진미,노재석,조은정
133. Perspective of mesenchymal transformation in glioblastoma
백선하*, Kim, Y , Verhaak, RGW , Varn, FS , Park, SH , Yoon, BW , Park, HR , Lee, C
132. p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis
권용태*,Lee, SH , Cho, WJ , Najy, AJ , Saliganan, AD , Pham, T , Rakowski, J , Loughery, B , Ji, CH , Sakr, W , Kim, S , Kato, I , Chung, WK , Kim, HE , Kim, HRC
131. Oxygen-dependent regulation of ion channels: acute responses, post-translational modification, and response to chronic hypoxia
김성준*,Yoo, HY
130. Opisthenar microvessel area as a sensitive predictive index of arterial stiffness in hypertensive patients
Yin Hua Zhang*,Guo, ZY , Chen, C , Jin, X , Zhao, ZH , Cui, L
129. O-GlcNAcylation of Sox2 at threonine 258 regulates the self-renewal and early cell fate of embryonic stem cells
윤홍덕*,신현무,Kim, DK , Lee, JS , Lee, EY , Jang, H , Han, S , Kim, HY , Hwang, IY , Choi, JW , You, HJ, Jang, H
128. Novel Drug Screening Platform: Tumor Organoid
맹주은, 서하영, 김순찬*, 구자록*
127. Novel cancer stem cell marker MVP enhances temozolomide-resistance in glioblastoma
예상규*,Noh, K. H.,Lee, S. H.,Lee, H.,Jeong, A. J.,Kim, K. O.,신현무,김항래,Park, M. J.,Park, J. B.,Lee, J.
126. Metastasis-on-a-chip reveals adipocyte-derived lipids trigger cancer cell migration via HIF-1 alpha activation in cancer cells
박종완*, 전양숙*, Jieun Seo,Kyeong Seog Kim,조주연,장학,Junji Fukuda,Ki Yong Hong
125. Kdm3b haploinsufficiency impairs the consolidation of cerebellum-dependent motor memory in mice
전양숙*,Kim, YG ,김상정,이용석, Bak, MS , Kim, A , Kim, Y , Chae, YC , Kim, YL , An, JY , Seo, SB
124. Intramolecular Disulfide Bonds for Biogenesis of CALHM1 Ion Channel Are Dispensable for Voltage-Dependent Activation
김성준*,Kwon, JW , Jeon, YK ,김상정, Kim, J
123. Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8+ T Cells, Resulting in Enhanced IL-1β Dependent Effector Function.
Dong Hyun Kim, Hee Young Kim, Won-Woo Lee*
122. Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells
Dong Hyun Kim, Hee Young Kim, Sunjung Cho, Su-Jin Yoo, Won-Ju Kim, Hye Ran Yeon, Kyungho Choi, Je-Min Choi, Seong Wook Kang, Won-Woo Lee*
121. How cancer cells remodel lipid metabolism: strategies targeting transcription factors
전양숙*,Jeong, DW , Lee, S
120. Higher expression of KCNK10 (TREK-2) K+ channels and their functional upregulation by lipopolysaccharide treatment in mouse peritoneal B1a cells
김성준*, 최성우*, , Woo, J , Park, KS , Ko, J , Jeon, YK , Choi, SW , Yoo, HY , Kho, I , Kim, TJ
119. Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts
Yin Hua Zhang*, 김성준*, Wu, Y. N.,Sudarshan, V. K.,Zhu, S. C.,Shao, Y. F.
118. Epithelial-to-mesenchymal transition in neutrophilic chronic rhinosinusitis
신현우*, Ryu, G, Mo, JH
117. Effect of lipopolysaccharide and polyinosinic:polycytidylic acid in a murine model of nasal polyp
신현우*, Wee, JH ,이재서,Ko, YK , Khalmuratova, R , Kim, DW
116. Effect of Lacticaseibacillus casei AMBR2 on Epithelial Barrier Function in Chronic Rhinosinusitis With Nasal Polyps
신현우*, Kim, Y. S.
115. Downregulation of Soluble Guanylate Cyclase and Protein Kinase G With Upregulated ROCK2 in the Pulmonary Artery Leads to Thromboxane A2 Sensitization in Monocrotaline-Induced Pulmonary Hypertensive Rats
김성준*,Cho, S , Namgoong, H , Kim, HJ , Vorn, R , Yoo, HY
114. DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition
박종완*, 신현우*, Lee, M.,Lim, S.,Kim, Y. S.,Khalmuratova, R.,Shin, S. H.,Kim, I.,김현직,김동영,이재서
113. Crosstalk Between Mucosal Inflammation and Bone Metabolism in Chronic Rhinosinusitis
신현우*, Khalmuratova R
112. Clinical outcome prediction from analysis of microelectrode recordings using deep learning in subthalamic deep brain stimulation for Parkinson`s disease
백선하*, Kim, HC ,Park, KH , Sun, S , Lim, YH , Park, HR , Lee, JM , Park, K , Jeon, B , Park, HP
111. Chromatin accessibility of circulating CD8 + T cells predicts treatment response to PD-1 blockade in patients with gastric cancer
예상규*,김항래,김광훈,김상집,심지현,신현무,이지연,최지엽,김민지,권민석,이동섭,조승우,김승태
110. Bone morphogenetic protein-2 as a novel biomarker for refractory chronic rhinosinusitis with nasal polyps
신현우*, 박종완*, Kim, JY , Lim, S ,Kim, DW , Lim, HS , Kim, YS , Eun, KM , Khalmuratova, R , Seo, Y , Kim, JK , Kim, YS , Kim, MK , Jin, SY , Han, SC , Pyo, S , Hong, SN
109. Antibiotic-Dependent Relationships Between the Nasal Microbiome and Secreted Proteome in Nasal Polyps
신현우*,Kim, Y. S.,Han, D.,Mo, J. H.,Kim, Y. M.,Kim, D. W.,Choi, H. G.,박종완
108. Activated Platelets Convert CD14 + CD16 - Into CD14 + CD16 + Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization
Su Jeong Lee, Bo Ruem Yoon, Hee Young Kim, Su-Jin Yoo, Seong Wook Kang, Won-Woo Lee*
107. Cardiac complex II activity is enhanced by fat and mediates greater mitochondrial oxygen consumption following hypoxic re-oxygenation.
Zhu S C , Chen C , Wu YN, Shao YF, Kim SJ, Zhang. YH*
106. Reduced nNOS activity is responsible for impaired fatty acid-dependent mitochondrial oxgen consumption in atrial myocardium from hypertensive rat hearts.
Wu YN, Jin CL,Jang JH,Zhao ZH,Kim SJ, Zhang YH*
105. Functional interactions between complexI and complex II with Nnos inregulating cardiac mitochondrial activity in sham and hypertensive rat hearts.
Wu YN, Sudarshan VK,Zhu SC, Shao YF,Kim SJ, Zhang YH*
104. Sleep Tests in the Non-Contact Era of the COVID-19 Pandemic: Home Sleep Tests Versus In-Laboratory Polysomnography
Dae Wui Yoon, Hyun-Woo Shin *
103. Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model
Roza Khalmuratova*, Mingyu Lee, Jong Wan Park*, Hyun Woo Shin*
102. Impact of the Long-Lived Plasma Cells in Patients With Chronic Rhinosinusitis With Nasal Polyps
Roza Khalmuratova*, Hyun-Woo Shin*
101. Crosstalk Between Mucosal Inflammation and Bone Metabolism in Chronic Rhinosinusitis
Roza Khalmuratova*, Hyun-Woo Shin*
100. Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD).
Kim HY, Lee SJ, Hwang Y, Lee GH, Yoon CE, Kim HC, Yoo TH, Lee WW*
99. Validation of CDr15 as a new dye for detecting neutrophil extracellular trap.
Kim SJ, Kim J, Kim B, Lee WW*, Liu X, Chang YT, Park JW*.
98. Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors.
Lee GH, Hong KT, Choi JY, Shin HY*, Lee WW*, Kang HJ.
97. Phosphorylation of OCT4 Serine 236 Inhibits Germ Cell Tumor Growth by Inducing Differentiation
Dong-Keon Kim, Bomin Song, Suji Han, Hansol Jang, Seung-Hyun Bae, Hee Yeon Kim, Seon-Hyeong Lee, Seungjin Lee, Jong Kwang Kim, Han-Seong Kim, Kyeong-Man Hong, Byung Il Lee, Hong-Duk Youn*, Soo-Youl Kim, Sang Won Kang, Hyonchol Jang
96. Regulation of reticulophagy by the N-degron pathway
Chang Hoon Ji , Hee Yeon Kim , Ah Jung Heo , Min Ju Lee , Daniel Youngjae Park , Dong Hyun Kim , Bo Yeon Kim , Yong Tae Kwon*
95. Tubulosine selectively inhibits JAK3 signaling by binding to the ATP-binding site of the kinase of JAK3.
Kim BH, Yi EH, Jee JG, Jeong AJ, Sandoval C, Park IC, Baeg GH, Ye SK*.
94. Crosstalk Between Prostate Cancer Cells and Tumor-Associated Fibroblasts Enhances the Malignancy by Inhibiting the Tumor Suppressor PLZF.
Noh KH, Jeong AJ, Lee H, Lee SH, Yi E, Chang PS, Kwak C, Ye SK.*
93. Extracellular Acidosis Promotes Metastatic Potency via Decrease of the BMAL1 Circadian Clock Gene in Breast Cancer.
Kwon YJ, Seo EB, Kwon SH, Lee SH, Kim SK, Park SK, Kim K, Park S, Park IC, Park JW*, Ye SK*.
92. STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model.
Kim BH, Lee H, Park CG, Jeong AJ, Lee SH, Noh KH, Park JB, Lee CG, Paek SH, Kim H, Ye SK*
91. Increased inward rectifier K+ current of coronary artery smooth muscle cells in spontaneously hypertensive rats; partial compensation of the attenuated endothelium-dependent relaxation via Ca2+ -activated K+ channels.
Kim HJ, Yin MZ, Cho S, Kim SE, Choi SW, Ye SK*, Yoo HY, Kim SJ
90. Dual regulatory effects of PI(4,5)P 2 on TREK-2 K +channel through antagonizing interaction between the alkaline residues (K 330 and R 355-357) in the cytosolic C-terminal helix
Sung Eun Kim , Myoung-Hwan Kim , Joohan Woo , Sung Joon Kim*
89. Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes
Seong Woo Choi* , Jin Soo Shin , Soon-Jung Park , Eunhye Jung , Yun-Gwi Park , Jiho Lee , Sung Joon Kim* , Hun-Jun Park , Jung-Hoon Lee , Sung-Min Park , Sung-Hwan Moon , Kiwon Ban , Yun Young Go
88. Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts
Yu Na Wu , Vidya K Sudarshan , Shi Chao Zhu , Yong Feng Shao , Sung Joon Kim* , Yin Hua Zhang*
87. Reduced nNOS activity is responsible for impaired fatty acid-dependent mitochondrial oxygen consumption in atrial myocardium from hypertensive rat
Yu Na Wu , Chun Li Jin , Ji Hyun Jang , Zai Hao Zhao , Sung Joon Kim* , Yin Hua Zhang*
86. Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes
Young Keul Jeon , Jae Boum Youm , Kotdaji Ha , JooHan Woo , Hae Young Yoo , Chae Hun Leem , Seung Hee Lee , Sung Joon Kim*
85. Decreased inward rectifier and voltage-gated K +currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats
Sung Eun Kim, Ming Zhe Yin , Hae Jin Kim , Rany Vorn , Hae Young Yoo , Sung Joon Kim*
84. Increased inward rectifier K + current of coronary artery smooth muscle cells in spontaneously hypertensive rats; partial compensation of the attenuated endothelium-dependent relaxation via Ca 2+ -activated K + channels
Hae Jin Kim , Ming Zhe Yin , Suhan Cho , Sung Eun Kim , Seong Woo Choi* , Sang Kyu Ye , Hae Young Yoo , Sung Joon Kim*
83. Brain tumor diagnostic model and dietary effect based on extracellular vesicle microbiome data in serum
Yang J, Moon HE, Park HW, McDowell A, Shin TS, Jee YK, Kym S, Paek SH*, Kim YK.
82. Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson's disease rat model
Park HW, Park CG, Park M, Lee SH, Park HR, Lim J, Paek SH*, Choy YB
81. Determination of Parkinson Disease Laterality After Deep Brain Stimulation Using I-123 FP-CIT SPECT
Park HR, Ha S, Lee DS, Im HJ, Paek SH*
80. STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model
Kim BH, Lee H, Park CG, Jeong AJ, Lee SH, Noh KH, Park JB, Lee CG, Paek SH*, Kim H, Ye SK
79. Magnetic and near-infrared derived heating characteristics of dimercaptosuccinic acid coated uniform Fe@Fe3O4 core-shell nanoparticles
Koo C, Hong H, Im PW, Kim H, Lee C, Jin X, Yan B, Lee W, Im HJ, Paek SH*, Piao Y
78. Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1
Jun Bum Park, Jieun Seo, Jong-Wan Park*, Yang-Sook Chun*
77. Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells
Jieun Seo, Do-Won Jeong, Jong-Wan Park*, Kwang-Woong Lee, Junji Fukuda, Yang-Sook Chun*
76. Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment
Uk-Il Ju, Do-Won Jeong, Jieun Seo, Jun Bum Park, Jong-Wan Park*, Kyung-Suk Suh, Jae Bum Kim, Yang-Sook Chun*
75. Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1
Jun Bum Park, Jieun Seo, Jong-Wan Park*, Yang-Sook Chun*
74. Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells
Jieun Seo, Do-Won Jeong, Jong-Wan Park*, Kwang-Woong Lee, Junji Fukuda, Yang-Sook Chun*
73. Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment
Uk-Il Ju, Do-Won Jeong, Jieun Seo, Jun Bum Park, Jong-Wan Park*, Kyung-Suk Suh, Jae Bum Kim, Yang-Sook Chun*
72. Validation of CDr15 as a new dye for detecting neutrophil extracellular trap.
Sang-Jin Kim , Jiyoung Kim , Bonah Kim , Won-Woo Lee , Xiao Liu , Young-Tae Chang , Jong-Wan Park*
71. Hypoxia-driven epigenetic regulation in cancer progression: A focus on histone methylation and its modifying enzymes.
Iljin Kim* , Jong-Wan Park*
70. Loss of EGR3 is an independent risk factor for metastatic progression in prostate cancer.
Seung-Hyun Shin , Iljin Kim* , Jae Eun Lee , Mingyu Lee , Jong-Wan Park*
69. Histone demethylase PHF2 activates CREB and promotes memory consolidation
Hye-Jin Kim, Sung Won Hur, Jun Bum Park, Jieun Seo, Jae Jin Shin, Seon-Young Kim, Myoung-Hwan Kim, Do Hyun Han, Jong-Wan Park*, Joo Min Park, Sang Jeong Kim, Yang-Sook Chun*
68. Senescent T Cells Predict the Development of Hyperglycemia in Humans
Lee YH, Kim SR, Han DH, Yu HT, Han YD, Kim JH, Kim SH, Lee CJ, Min BH, Kim DH, Kim KH, Cho JW, Lee WW*, Shin EC, Park S
67. Interaction between microglia and retinal pigment epithelial cells determines the integrity of outer blood-retinal barrier in diabetic retinopathy
Jo DH, Yun JH, Cho CS, Kim JH, Kim JH*, Cho CH*
66. Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model
Yoon DW, Kim YS, Hwang S, Khalmuratova R*, Lee M, Kim JH, Lee GY, Koh SJ, Park JW*, Shin HW
65. Triple arginine residues in the proximal C-terminus of TREK K(+) channels are critical for biphasic regulation by phosphatidylinositol 4,5-bisphosphate
Woo J, Jeon YK, Zhang YH*, Nam JH, Shin DH, Kim SJ*
64. Suppression of Syk activation by resveratrol inhibits MSU crystal-induced inflammation in human monocytes
Chung YH, Kim HY, Yoon BR, Kang YJ, Lee WW*
63. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells
Kim I, Shin SH, Lee JE, Park JW*
62. The IFN-γ-p38, ERK kinase axis exacerbates neutrophilic chronic rhinosinusitis by inducing the epithelial-to-mesenchymal transition
Lee M, Kim DW, Khalmuratova R*, Shin SH, Kim YM, Han DH, Kim HJ, Kim DY, Rhee CS, Park JW*, Shin HW
61. Nuclear FGFR2 negatively regulates hypoxia-induced cell invasion in prostate cancer by interacting with HIF-1 and HIF-2
Lee JE, Shin SH, Shin HW, Chun YS*, Park JW*
60. Endurance exercise training restores atrophy-induced decreases of myogenic response and ionic currents in rat skeletal muscle artery
Yin MZ, Kim HJ, Suh EY, Zhang YH*, Yoo HY, Kim SJ*
59. Evaluation and Optimization of the Anti-Melanogenic Activity of 1-(2-Cyclohexylmethoxy-6-hydroxy-phenyl)-3-(4-hydroxymethyl-phenyl)-propenone Derivatives
Kim BH, Hong SN, Ye SK*, Park JY
58. A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy
Yi HG*, Jeong YH, Kim Y, Choi YJ, Moon HE, Park SH, Kang KS, Bae M, Jang J, Youn H, Paek SH*, Cho DW
57. Highlighted STAT3 as a Potential Drug Target for Cancer Therapy Cancer Therapy
Lee H, Jeong AJ, Ye SK*
56. A new stone for a new path, from "physiology to the bedside"
Zhang YH*, Han J
55. Optimization and validation of a method to identify skin sensitization hazards using IL-1 α and IL-6 secretion from HaCaT sensitization hazards using IL-1 α and IL-6 secretion from HaCaT
Jeon B, Kim MO, Kim YS, Han HY, Yun JH, Kim J, Huang Y, Choi Y, Cho CH*, Kang BC, Kim S, Choi TH
54. A novel HIF1AN substrate KANK3 plays a tumor-suppressive role in hepatocellular carcinoma
Kim I, Kang J, Gee HY, Park JW*
53. Effects of Recovery Time during Magnetic Nanofluid Hyperthermia on the Induction Behavior and Efficiency of Heat Shock Proteins 72
Jang JT, Jeoung JW, Park JH, Lee WJ, Kim YJ, Seon J, Kim M, Lee J, Paek SH*, Park KH, Bae S
52. FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Kang J, Shin SH, Yoon H, Huh J, Shin HW, Chun YS*, Park JW*
51. Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway
Cha-Molstad H, Lee SH, Kim JG, Sung KW, Hwang J, Shim SM*, Ganipisetti S, McGuire T, Mook-Jung I, Ciechanover A, Xie XQ, Kim BY, Kwon YT*
50. β-Adrenergic receptor agonists attenuate pericyte loss in diabetic retinas through Akt activation
Yun JH, Jeong HS, Kim KJ, Han MH, Lee EH*, Lee K, Cho CH*
49. The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation
Shim SM*, Choi HR, Sung KW, Lee YJ, Kim ST, Kim D, Mun SR, Hwang J, Cha-Molstad H, Ciechanover A, Kim BY, Kwon YT*
48. Inhibition of neddylation facilitates cell migration through enhanced phosphorylation of caveolin-1 in PC3 and U373MG cells
Park SY*, Park JW*, Lee GW, Li L, Chun YS*
47. Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses
Yoon BR, Oh YJ, Kang SW, Lee EB, Lee WW*
46. N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT*
45. Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway
Jin P, Shin SH, Chun YS*, Shin HW, Shin YJ, Lee Y, Kim D, Nam DH, Park JW*
44. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH
Jin P, Kang J, Lee MK, Park JW*
43. S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes
Jeong EM, Jin CZ, Jang JH, Zhao ZH, Jin CL, Lee JH, Lee KB, Kim SJ*, Kim IG, Zhang YH*
42. CST3 and GDF15 ameliorate renal fibrosis by inhibiting fibroblast growth and activation
Kim YI, Shin HW, Chun YS*, Park JW*
41. Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression
Khalmuratova R*, Lee M, Mo JH, Jung Y, Park JW*, Shin HW
40. Epithelial cell-derived cytokines CST3 and GDF15 as potential therapeutics for pulmonary fibrosis
Kim YI, Shin HW, Chun YS*, Cho CH*, Koh J, Chung DH*, Park JW*
39. NDRG3 lowers the metastatic potential in prostate cancer as a feedback controller of hypoxia-inducible factors
Lee GY, Shin SH, Shin HW, Chun YS*, Park JW*
38. Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense
So D, Shin HW, Kim J, Lee M, Myeong J, Chun YS*, Park JW*
37. Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation
Kwak S, Kim TW, Kang BH, Kim JH*, Lee JS, Lee HT, Hwang IY*, Shin J, Lee JH, Cho EJ, Youn HD*
36. Abundance of C-terminal binding protein isoform is a prerequisite for exit from pluripotency in mouse embryonic stem cells
Suh MY, Kim TW, Lee HT, Shin J, Kim JH, Jang H, Kim HJ, Kim ST, Cho EJ, Youn HD*
35. The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src
Lee GW, Park JB, Park SY*, Seo J, Shin SH, Park JW*, Kim SJ, Watanabe M, Chun YS*
34. Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells
Kim HJ, Shin J, Lee S, Kim TW, Jang H, Suh MY, Kim JH*, Hwang IY*, Hwang DS, Cho EJ, Youn HD*
33. PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
Lee DH, Kim D, Kim ST, Jeong S, Kim JL, Shim SM*, Heo AJ, Song X, Guo ZS, Bartlett DL, Oh SC, Lee J, Saito Y, Kim BY, Kwon YT*, Lee YJ
32. Oleanolic Acids Inhibit Vascular Endothelial Growth Factor Receptor 2 Signaling in Endothelial Cells: Implication for Anti-Angiogenic Therapy
Lee DH, Lee J, Jeon J, Kim KJ, Yun JH, Jeong HS, Lee EH, Koh YJ, Cho CH*
31. Propranolol increases vascular permeability through pericyte apoptosis and exacerbates oxygen-induced retinopathy
Yun JH, Koh YJ, Jeong HS, Lee DH, Lee EH, Cho CH*
30. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome
Kim ST, Lee YJ, Tasaki T, Mun SR, Hwang J, Kang MJ, Ganipisetti S, Yi EC, Kim BY, Kwon YT*
29. The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins
Kim ST, Lee YJ, Tasaki T, Hwang J, Kang MJ, Yi EC, Kim BY, Kwon YT*
28. FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
Kang J, Chun YS*, Huh J, Park JW*
27. Retinal pigment epithelium-derived transforming growth factor-β2 inhibits the angiogenic response of endothelial cells by decreasing vascular endothelial growth factor receptor-2 expression
Jeong HS, Yun JH, Lee DH, Lee EH, Cho CH*
26. Microgravity induces autophagy via mitochondrial dysfunction in human Hodgkin's lymphoma cells
Jeong AJ, Kim YJ, Lim MH, Lee H, Noh K, Kim BH, Chung JW, Cho CH*, Kim S, Ye SK*
25. Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway
Shin SH, Lee GY, Lee M, Kang J, Shin HW, Chun YS*, Park JW*
24. Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization
Park J, Lee H, Han N, Kwak S, Lee HT, Kim JH*, Kang K, Youn BH, Yang JH, Jeong HJ, Kang JS, Kim SY, Han JW, Youn HD*, Cho EJ
23. Delayed facial palsy after microvascular decompression for hemifacial spasm: friend or foe?
Lee JM, Park HR, Choi YD, Kim SM, Jeon B, Kim HJ, Kim DG, Paek SH*.
22. FIH is an oxygen sensor in ovarian cancer for G9a/GLP-driven epigenetic regulation of metastasis-related genes
Jengmin Kang, Seung-Hyun Shin, Haejin Yoon, June Huh, Hyun-Woo Shin*, Yang-Sook Chun*, Jong-Wan Park*
21. Accelerated tumor growth under intermittent hypoxia is associated with hypoxia-inducible factor-1-dependent adaptive responses to hypoxia
Dae Wui Yoon,, Daeho So, Sra Min, Jiyoung Kim, Mingyu Lee, Roza Khalmuratova, Chung-Hyun Cho*, Jong-Wan Park*, Hyun-Woo Shin*
20. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway, which modulates autophagosome biogenesis.
Cha-Molstad, H, J.E. Yu, Z. Feng, S.H. Lee, J.G. Kim, P. Yang, B. Han, K.W. Sung, Y.D. Yoo, J. Hwang, T. McGuire, S.M. Shim, H.D. Song, S. Ganipisetti, N. Wang, J.M. Jang, M.J. Lee, S.J. Kim, K.H. Lee, J.T. Hong, A. Ciechanover, I. Mook-Jung, K.P. Kim, X-.Q. Xie, Y.T. Kwon*, and B.Y. Kim*.
Nat. Comms.,
2017,
8,
102
SCI(E)
19. Sinonasal Delivery of Resveratrol via Mucoadhesive Nanostructured Microparticles in a Nasal Polyp Mouse Model
Mingyu Lee, Chun Gwon Park, Beom Kang Huh, Se-Na Kim, Seung Ho Lee, Roza Khalmuratova, Jong-Wan Park*, Hyun-Woo Shin*, Young Bin Choy*
Scientific Reports,
2017,
7,
40249
SCI(E)
18. Indoxyl sulfate (IS)-mediated immune dysfunction provokes endothelial damage in patients with end-stage renal disease (ESRD)
Kim HY, Yoo TH, Hwang Y, Lee GH, Kim B, Jang J, Yu HT, Kim MC, Cho JY, Lee CJ,Kim HC, Park S, Lee WW*
Sci Rep.,
2017,
7,
1,
3057
SCI(E)
17. FOXO1 reduces tumorsphere formation capacity and has crosstalk with LGR5 signaling in gastric cancer cells.
Yiseul Choi, Jinju Park, Young San Ko, Younghoon Kim, Jung-Soo Pyo, Bo Gun Jang, Min A Kim, Jae-Seon Lee, Mee Soo Chang, Byung Lan Lee*
Biochem Biophys Res Commun.,
2017,
493,
3,
1349-1355.
SCI(E)
16. Ctbp2-mediated β-catenin regulation is required for exit from pluripotency
Kim TW, Kwak S, Shin J, Kang BH, Lee SE, Suh MY, Kim JH*, Hwang IY, Lee JH, Choi J, Cho EJ, Youn HD*.
Nature Publishing Group,
2017,
49,
10,
e385
SCI(E)
15. Dysfunction of Microglial STAT3 Alleviates Depressive Behavior via Neuron-Microglia Interactions.
Kwon SH*, Han JK, Choi M, Kwon YJ, Kim SJ, Yi EH, Shin JC, Cho IH, Kim BH*, Jeong Kim S*, Ye SK*
Neuropsychopharmacology,
2017,
42,
10,
2072-2086
SCI(E)
14. The Ubiquitin code in the ubiquitin-proteasome system and autophagy.
A. Ciechanover and Y.T. Kwon*.
Trends in Biochem. Sci.,
2017,
42,
873-886
SCI(E)
13. Crosstalk and interplay between the ubiquitin-proteasome system and autophagy.
Ji, C.H*. and Y.T. Kwon*.
Mol Cells.,
2017,
40,
441-449
SCI(E)
12. STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression
Kim KJ, Kwon SH, Yun JH, Jeong HS, Kim HR*, Lee EH*, Ye SK*, Cho CH*.
Oncogene,
2017,
36,
39,
5445-5459
SCI(E)
11. Effect of Single and Double Administration of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Focal Cerebral Ischemia in Rats
Park HW, Kim Y, Chang JW, Yang YS, Oh W, Lee JM, Park HR, Kim DG, Paek SH*.
Experimental Neurobiology,
2017,
26,
1,
55-65
SCI(E)
10. Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy.
Yun JH, Park SW, Kim KJ, Bae JS, Lee EH, Paek SH*, Kim SU, Ye S*, Kim JH*, Cho CH*.
J Cell Physiol,
2017,
232,
5,
1123-1134
SCI(E)
9. Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition.
Young Dong Yoo*, Dae-Hee Lee, Hyunjoo Cha-Molstad, Hyungsin Kim, Su Ran Mun, Changhoon Ji, Seong Hye Park, KiSa Sung, SeungAh Choi, Joonsung Hwang, Deric M. Park, Seung-Ki Kim, Kyung-Jae Park, Shin-Hyuk Kang, Sang Cheul Oh, Aaron Ciechanover, YongJ. Lee, BoYeon Kim, and YongTae Kwon*.
EMBO Reports,
2017,
18,
150-168
SCI(E)
8. Immune Cell Responses and Mucosal Barrier Disruptions in Chronic Rhinosinusitis
Roza Khalmuratova, Jong-Wan Park*, Hyun-Woo Shin*
Immune Network,
2017,
17,
1,
60-67
7. Targeting IL-25 as a novel therapy in chronic rhinosinusitis with nasal polyps.
Mingyu Lee, Dae Woo Kim*, Hyun-Woo Shin*
Current Opinion in Allergy and Clinical Immunology,
2017,
17,
1,
17-22
SCI(E)
6. Time-averaged simulated microgravity (taSMG) inhibits proliferation of lymphoma cells, L-540 and HDLM-2, using a 3D clinostat.
Kim YJ, Jeong AJ, Kim M, Lee C, Ye SK*, Kim S*
Biomed Eng Online.,
2017,
16,
1,
48
SCI(E)
5. Urinary Metabolomic Signatures in Obstructive Sleep Apnea through Targeted Metabolomic Analysis: A Pilot Study
Kumsun Cho, Dae Wui Yoon, Mingyu Lee, Daeho So, Il‑Hee Hong, Chae‑Seo Rhee*, Jong‑Wan Park*, Joo‑Youn Cho*, Hyun‑Woo Shin*
4. Protein quality control by molecular chaperones in neurodegeneration.
A. Ciechanover and Y.T. Kwon*.
3. Role of muscular eNOS in skeletal arteries: Endothelium-independent hypoxic vasoconstriction of the femoral artery is impaired in eNOS-deficient mice
Kim HJ, Yoo HY*, Lin HY, Oh GT, Zhang YH*, Kim SJ*
2. Negligible effect of eNOS palmitoylation on fatty acid regulation of contraction in ventricular myocytes from healthy and hypertensive rats
Jin CL, Wu YN, Jang JH, Zhao ZH, Oh GT, Kim SJ*, Zhang YH*
1. Neuronal nitric oxide synthase modulation of intracellular Ca(2+) handling overrides fatty acid potentiation of cardiac inotropy in hypertensive rats
Jin CL, Yin MZ, Paeng JC, Ha S, Lee JH, Jin P, Jin CZ, Zhao ZH, Wang Y, Kang KW, Leem CH*, Park JW*, Kim SJ*, Zhang YH*