- 연자 :  김지현 교수님(Deakin University School of Medicine, Australia)
- 제목 :  Tentative title: Development and maturation as periods of vulnerability and opportunity in memory and forgetting 
- 일시 :  2025년 3월 13일 목요일 12시(정오)
- 장소 :  연구관 708호 회의실

Jee Hyun Kim 
Professor, School of Medicine, Deakin University
Australian Research Council (ARC) Future Fellow
Head of Molecular Psychiatry Laboratory
IMPACT, the Institute for Mental and Physical Health and Clinical Translation
School of Medicine Deakin University

Description: 
Learning and memory are fundamental features of humans adapting to an everchanging environment. They have been extensively studied and we have progressed significantly in our psychological and biological understanding of their role in mental disorders. In contrast, the role of forgetting is a recent topic of interest, with the increasing recognition that “to understand how we remember, we must also understand how, and why, we forget”. For example, the ability to forget helps us to adapt by focusing on the present and be creative. Importantly, forgetting allows us to manage living with ghosts from the past. My vision is to understand the role of memory and forgetting across the lifetime in mental disorders and to translate the findings into the clinic. I believe the key to finding effective treatments lies in how we remember and forget emotionally significant events during our development. We use various rodent models that closely resemble human behaviors, and manipulate them using different drugs, viruses, and behavioral approaches to find potential therapeutics. We discovered that behavioral training that normally reduces anxiety and drug seeking in adult rodents are not effective during adolescence. These findings have since been replicated in humans and we are now investigating how we can reverse such impairments by understanding and manipulating the neuropharmacological basis of early life vulnerability in mental disorders.

 Bio:
Professor Jee Hyun Kim is an Australian Research Council Future Fellow and the Head of Molecular Psychiatry Laboratory at the School of Medicine, Deakin University. Jee graduated with 1^st class Honours and the University medal in Bachelor of Psychology from the University of New South Wales (Sydney, Australia). After obtaining her PhD, Jee received postdoctoral training at University of Michigan (Ann Arbor, USA) before her appointment at the University of Melbourne in 2011. Jee joined Deakin University in 2020. Jee studies the neurobiology of memory and forgetting in mental disorders across development and ageing in rodents and humans, with a strong cognition and translation focus. Apart from basic neuroscience work in memory, Jee is currently managing the Trimetazidine In bipolar DEpression (TIDE) clinical trial to test the efficacy of a metabolic drug on reducing depression in bipolar disorder. Jee has won numerous national and international awards for her ground-breaking work (https://en.wikipedia.org/wiki/Jee_Hyun_Kim), including the World Federation of Societies of Biological Psychiatry Young Investigator Award in 2024. Jee has >100 publications, for which she is the corresponding author to >60. Citations are >4,000. Jee is an active science communicator, with her TEDxMelbourne talk reaching >800,000 views (https://www.youtube.com/watch?v=W_t9O5MgisM). Jee strongly believes in open science and collaborations to actively combat the replication crisis in science. For example, she has been leading mapping of dopamine receptors (DOPAMAP) across development in male and female mice in partnership with the Human Brain Project funded by European Union (https://www.humanbrainproject.eu/en/about/project-structure/partnering-projects/dopamap/).

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