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• 연자 : 최지원 박사(Department of Biology New York University)
• 제목 : Retinal Calcium Waves as a Tissue-Level Mechanism for Neurodevelopment and Regeneration
• 일시 : 2026년 1월 21일(수) 12시(정오)
• 장소 : 연구관 708호 회의실

Abstract:
Spontaneous calcium waves are a conserved feature of developing tissues, yet how they organize tissue structure and function remains poorly understood. In this talk, I will describe how retinal calcium waves propagate through a gap-junction network among non-neuronal cells in the Drosophila eye. These waves function as a tissue-level mechanism by generating retina-wide patterned calcium activity. This spatially organized signaling drives regionalized morphogenesis and matched retina-brain circuit assembly required for normal visual system development. I will also discuss emerging evidence that gap-junction-mediated calcium waves are redeployed during retinal injury responses. These responses parallel calcium wave signaling observed in mammalian injury models and highlight conserved principles of calcium wave-mediated multicellular coordination in neurodevelopment and regeneration.